At the Dagstuhl Seminar on Security of Machine Learning in July 2022, experts from all over the world met to discuss research trends and future directions for research in protecting ML-based systems. The seminar featured a mix of academics, young researchers, and industry practitioners. Despite the relaxed atmosphere, the seminar inspired diverse questions—among which, a recurring theme entailed the practical relevance of related research. For example, should industry truly be worried about the attacks portrayed in research papers, and are the assumptions made in research truly representative of the real world?